Research

The human brain uses about 25% of the human body’s metabolic energy and is particularly sensitive to the aging process. A growing number of scientists are looking into the contributions of mitochondria in brain health with preliminary studies suggesting they could be key players in brain disorders.

A 2018 report reviewed recent evidence implicating mitochondrial dysfunction in the development of heart failure. “Oxidative metabolism in mitochondria is the main energy source of the heart, and the inability to generate and transfer energy has long been considered the primary mechanism linking mitochondrial dysfunction and contractile failure.”

During strenuous exercise, the rate of energy use in skeletal muscles can increase by more than 100-fold almost instantly. To meet this energy demand, muscle cells contain mitochondria. Our clinical studies have shown improved muscle strength and endurance as a result of improved mitochondrial function.

Joints are key for our mobility. The cells required to keep our joints functional progressively decline in function, and so do their mitochondria. These powerhouses need to be renewed and nourished to keep our joints healthy. There is emerging science around the link between mitochondria and arthritis.

The immune system protects us from infections and from excessive inflammation. With age, its control loosens up. Evidence is rising on the importance of mitochondria to reduce inflammation with aging, also known as inflamm-aging.

The digestive system is essential to human well-being. Mitochondrial health has been associated with improved gut barrier health, a reduced risk of fatty liver disease, improved kidney function and lower risk of glucose intolerance.